diff --git a/.changeset/quiet-submit-guard.md b/.changeset/quiet-submit-guard.md
new file mode 100644
index 0000000000..cd05ad2fdb
--- /dev/null
+++ b/.changeset/quiet-submit-guard.md
@@ -0,0 +1,5 @@
+---
+'@tanstack/form-core': patch
+---
+
+Prevent concurrent form submissions while an async submit is already in progress.
diff --git a/packages/form-core/src/FormApi.ts b/packages/form-core/src/FormApi.ts
index 4400017d30..f0bfe56e10 100644
--- a/packages/form-core/src/FormApi.ts
+++ b/packages/form-core/src/FormApi.ts
@@ -2418,6 +2418,8 @@ export class FormApi<
    * Handles the form submission, performs validation, and calls the appropriate onSubmit or onSubmitInvalid callbacks.
    */
   _handleSubmit = async (submitMeta?: TSubmitMeta): Promise<void> => {
+    if (this.state.isSubmitting) return
+
     this.baseStore.setState((old) => ({
       ...old,
       // Submission attempts mark the form as not submitted
diff --git a/packages/form-core/tests/FormApi.spec.ts b/packages/form-core/tests/FormApi.spec.ts
index c57bb044e8..f3aa9f0695 100644
--- a/packages/form-core/tests/FormApi.spec.ts
+++ b/packages/form-core/tests/FormApi.spec.ts
@@ -3521,6 +3521,38 @@ describe('form api', () => {
     expect(form.state.isSubmitSuccessful).toBe(false)
   })
 
+  it('should not call onSubmit again while a submission is in progress', async () => {
+    vi.useFakeTimers()
+    try {
+      const submitDelayMs = 1000
+      const expectedSubmitCount = 1
+      const onSubmit = vi.fn(async () => {
+        await sleep(submitDelayMs)
+      })
+      const form = new FormApi({
+        defaultValues: {
+          name: 'test',
+        },
+        onSubmit,
+      })
+
+      form.mount()
+
+      const firstSubmit = form.handleSubmit()
+      await vi.advanceTimersByTimeAsync(0)
+
+      const secondSubmit = form.handleSubmit()
+      await vi.advanceTimersByTimeAsync(0)
+
+      expect(onSubmit).toHaveBeenCalledTimes(expectedSubmitCount)
+
+      await vi.runAllTimersAsync()
+      await Promise.all([firstSubmit, secondSubmit])
+    } finally {
+      vi.useRealTimers()
+    }
+  })
+
   it('should reset the fields value and meta to default state', async () => {
     const form = new FormApi({
       defaultValues: {