diff --git a/Lib/_pyrepl/__init__.py b/Lib/_pyrepl/__init__.py
index 1693cbd0b98b74c..6b2328893d92441 100644
--- a/Lib/_pyrepl/__init__.py
+++ b/Lib/_pyrepl/__init__.py
@@ -17,3 +17,9 @@
 # RESULTING FROM LOSS OF USE, DATA OR PROFITS, WHETHER IN AN ACTION OF
 # CONTRACT, NEGLIGENCE OR OTHER TORTIOUS ACTION, ARISING OUT OF OR IN
 # CONNECTION WITH THE USE OR PERFORMANCE OF THIS SOFTWARE.
+
+from collections.abc import Callable as _Callable
+
+
+# Declared here so external tools can detect support and install a callback.
+pre_execution_hook: _Callable[[str], object] | None = None
diff --git a/Lib/_pyrepl/simple_interact.py b/Lib/_pyrepl/simple_interact.py
index e6c355388a7c074..d7f864d20f43db8 100644
--- a/Lib/_pyrepl/simple_interact.py
+++ b/Lib/_pyrepl/simple_interact.py
@@ -30,6 +30,8 @@
 import code
 import warnings
 
+import _pyrepl
+
 from .readline import _get_reader, multiline_input, append_history_file
 
 
@@ -145,6 +147,13 @@ def maybe_run_command(statement: str) -> bool:
             if maybe_run_command(statement):
                 continue
 
+            pre_execution_hook = getattr(_pyrepl, "pre_execution_hook", None)
+            if callable(pre_execution_hook):
+                try:
+                    pre_execution_hook(statement)
+                except Exception:
+                    pass
+
             input_name = f"<python-input-{input_n}>"
             more = console.push(_strip_final_indent(statement), filename=input_name, _symbol="single")  # type: ignore[call-arg]
             assert not more
diff --git a/Lib/test/test_pyrepl/test_interact.py b/Lib/test/test_pyrepl/test_interact.py
index fd4530ebc004aa7..d5ba6a30ae97938 100644
--- a/Lib/test/test_pyrepl/test_interact.py
+++ b/Lib/test/test_pyrepl/test_interact.py
@@ -2,9 +2,11 @@
 import io
 import warnings
 import unittest
-from unittest.mock import patch
+from unittest.mock import MagicMock, patch
 from textwrap import dedent
 
+import _pyrepl
+
 from test.support import force_not_colorized
 
 from _pyrepl.console import InteractiveColoredConsole
@@ -299,3 +301,70 @@ def f():
         count = sum("'return' in a 'finally' block" in str(w.message)
                     for w in caught)
         self.assertEqual(count, 1)
+
+
+class TestPreExecutionHook(unittest.TestCase):
+
+    def test_hook_is_unset_by_default(self):
+        self.assertIsNone(_pyrepl.pre_execution_hook)
+
+    def _run_interactive(self, statements, *, pre_execution_hook=None):
+        from _pyrepl.simple_interact import run_multiline_interactive_console
+
+        console = InteractiveColoredConsole()
+        statement_iter = iter(statements)
+
+        def fake_multiline_input(more_lines, ps1, ps2):
+            try:
+                return next(statement_iter)
+            except StopIteration:
+                raise EOFError
+
+        patches = [
+            patch(
+                "_pyrepl.simple_interact.multiline_input",
+                side_effect=fake_multiline_input,
+            ),
+            patch("_pyrepl.simple_interact._get_reader"),
+            patch("_pyrepl.simple_interact.append_history_file"),
+            patch("_pyrepl.readline._setup"),
+        ]
+        if pre_execution_hook is not None:
+            patches.append(
+                patch.object(
+                    _pyrepl,
+                    "pre_execution_hook",
+                    pre_execution_hook,
+                )
+            )
+
+        output = io.StringIO()
+        with contextlib.ExitStack() as stack:
+            for context_manager in patches:
+                stack.enter_context(context_manager)
+            stack.enter_context(contextlib.redirect_stdout(output))
+            stack.enter_context(contextlib.redirect_stderr(output))
+            run_multiline_interactive_console(console)
+
+        return output.getvalue(), console.locals
+
+    def test_hook_called_with_statement(self):
+        hook = MagicMock()
+        self._run_interactive(["x = 1"], pre_execution_hook=hook)
+        hook.assert_called_once_with("x = 1")
+
+    def test_hook_exception_does_not_break_repl(self):
+        hook = MagicMock(side_effect=RuntimeError("hook error"))
+        output, namespace = self._run_interactive(
+            ["x = 1", "y = 2"],
+            pre_execution_hook=hook,
+        )
+        self.assertEqual(hook.call_count, 2)
+        self.assertEqual(namespace["x"], 1)
+        self.assertEqual(namespace["y"], 2)
+        self.assertNotIn("hook error", output)
+
+    def test_hook_not_called_for_repl_commands(self):
+        hook = MagicMock()
+        self._run_interactive(["clear"], pre_execution_hook=hook)
+        hook.assert_not_called()
diff --git a/Misc/NEWS.d/next/Library/2026-09-09-23-15-03.gh-issue-122622.YfSSrl.rst b/Misc/NEWS.d/next/Library/2026-09-09-23-15-03.gh-issue-122622.YfSSrl.rst
new file mode 100644
index 000000000000000..c73e9e45c01454c
--- /dev/null
+++ b/Misc/NEWS.d/next/Library/2026-09-09-23-15-03.gh-issue-122622.YfSSrl.rst
@@ -0,0 +1,3 @@
+Add an optional ``_pyrepl.pre_execution_hook`` callable that is invoked with
+the submitted source before each interactive statement is executed. This
+allows external tools to implement features such as shell integration.