diff --git a/packages/react-native-babel-preset/src/__tests__/inline-platform-opt-in-test.js b/packages/react-native-babel-preset/src/__tests__/inline-platform-opt-in-test.js
new file mode 100644
index 000000000000..f47ee84146a0
--- /dev/null
+++ b/packages/react-native-babel-preset/src/__tests__/inline-platform-opt-in-test.js
@@ -0,0 +1,103 @@
+/**
+ * Copyright (c) Meta Platforms, Inc. and affiliates.
+ *
+ * This source code is licensed under the MIT license found in the
+ * LICENSE file in the root directory of this source tree.
+ *
+ * @flow strict-local
+ * @format
+ */
+
+'use strict';
+
+// $FlowExpectedError[untyped-import] - Preset is untyped
+const preset = require('../index');
+const babel = require('@babel/core');
+
+const FILENAME = '/app/src/App.js';
+const SRC = "import {Platform} from 'react-native';\nconst os = Platform.OS;";
+
+type PresetOptions = {
+  platform?: ?string,
+  inlinePlatform?: boolean,
+};
+
+type CallerOptions = {
+  platform?: ?string,
+  inlinePlatform?: boolean,
+};
+
+function transform({
+  presetOptions = {},
+  caller = {},
+}: {
+  presetOptions?: PresetOptions,
+  caller?: CallerOptions,
+} = {}): string {
+  const result = babel.transformSync(SRC, {
+    babelrc: false,
+    caller: {name: 'test', ...caller},
+    compact: false,
+    configFile: false,
+    filename: FILENAME,
+    presets: [[preset, {dev: false, ...presetOptions}]],
+    sourceMaps: false,
+  });
+  const code = result?.code;
+  if (code == null) {
+    throw new Error('Expected the transform to produce code');
+  }
+  return code;
+}
+
+function isInlined(code: string): boolean {
+  return code.includes('"ios"') && !/\.OS\b/.test(code);
+}
+
+describe('Platform inlining is opt-in', () => {
+  test('does not inline when only a platform is given', () => {
+    // A platform on its own says which platform we are compiling *for*. It is
+    // also set by consumers that need platform-correct module resolution but
+    // must keep `Platform` observable at runtime - Jest mocks it.
+    expect(isInlined(transform({presetOptions: {platform: 'ios'}}))).toBe(
+      false,
+    );
+  });
+
+  test('does not inline when only the Babel caller gives a platform', () => {
+    expect(isInlined(transform({caller: {platform: 'ios'}}))).toBe(false);
+  });
+
+  test('inlines when opted in via preset options', () => {
+    expect(
+      isInlined(
+        transform({presetOptions: {platform: 'ios', inlinePlatform: true}}),
+      ),
+    ).toBe(true);
+  });
+
+  test('inlines when opted in via the Babel caller', () => {
+    // The only channel available when the preset is named in a babel.config.js,
+    // where Babel supplies no preset options.
+    expect(
+      isInlined(transform({caller: {platform: 'ios', inlinePlatform: true}})),
+    ).toBe(true);
+  });
+
+  test('preset options take precedence over the caller', () => {
+    expect(
+      isInlined(
+        transform({
+          presetOptions: {inlinePlatform: false},
+          caller: {platform: 'ios', inlinePlatform: true},
+        }),
+      ),
+    ).toBe(false);
+  });
+
+  test('opting in without a platform is still a no-op', () => {
+    expect(isInlined(transform({presetOptions: {inlinePlatform: true}}))).toBe(
+      false,
+    );
+  });
+});
diff --git a/packages/react-native-babel-preset/src/configs/main.js b/packages/react-native-babel-preset/src/configs/main.js
index d1f9491d142f..a48b126ca8b8 100644
--- a/packages/react-native-babel-preset/src/configs/main.js
+++ b/packages/react-native-babel-preset/src/configs/main.js
@@ -48,16 +48,18 @@ function getTransformProfile(caller) {
   return caller?.unstable_transformProfile ?? 'hermes-stable';
 }
 
-// The target platform for `Platform.OS` / `Platform.select` inlining. Metro
-// passes this in transform options; when the preset is consumed directly as a
-// Babel preset (no `options.platform`), fall back to the Babel caller so any
-// Metro-driven consumer (bare Metro, Expo, @fb-tools/transformer) works without
-// extra wiring. Reading it via `babel.caller` also makes Babel re-evaluate the
-// preset when the platform changes between transform calls.
+// The target platform, currently only used for platform inlining.
 function getPlatform(caller) {
   return caller?.platform ?? null;
 }
 
+// Boolean, whether to inline `Platform`. Separate from `platform` (string)
+// because a platform already reaches the preset and may be used for other
+// purposes.
+function getInlinePlatform(caller) {
+  return caller?.inlinePlatform ?? false;
+}
+
 // use `this.foo = bar` instead of `this.defineProperty('foo', ...)`
 const loose = true;
 
@@ -69,6 +71,9 @@ const getPreset = (src, options, babel) => {
 
   const platform = options?.platform ?? babel?.caller(getPlatform);
 
+  const inlinePlatform =
+    options?.inlinePlatform ?? babel?.caller(getInlinePlatform) ?? false;
+
   // Hermes V1 uses more optimised transform profiles. There is currently no
   // difference between stable and canary, but canary may in future be used to
   // test features in pre-prod Hermes V1 versions.
@@ -121,7 +126,9 @@ const getPreset = (src, options, babel) => {
   // `disableImportExportTransform` is set), while the source-level import that
   // proves provenance is still intact. It is a no-op when `platform` is null or
   // the empty string.
-  extraPlugins.push([require('../inline-platform-plugin'), {platform}]);
+  if (inlinePlatform) {
+    extraPlugins.push([require('../inline-platform-plugin'), {platform}]);
+  }
 
   if (!options.useTransformReactJSXExperimental) {
     extraPlugins.push([
diff --git a/packages/react-native-babel-transformer/src/__tests__/inline-platform-integration-test.js b/packages/react-native-babel-transformer/src/__tests__/inline-platform-integration-test.js
index 22ce30319d52..dfbf52083153 100644
--- a/packages/react-native-babel-transformer/src/__tests__/inline-platform-integration-test.js
+++ b/packages/react-native-babel-transformer/src/__tests__/inline-platform-integration-test.js
@@ -30,10 +30,12 @@ function transformToCode(
     filename = path.join(PROJECT_ROOT, 'App.js'),
     platform = 'ios',
     experimentalImportSupport = false,
+    inlinePlatform = true,
   }: {
     filename?: string,
     platform?: ?string,
     experimentalImportSupport?: boolean,
+    inlinePlatform?: boolean,
   } = {},
 ): string {
   const {transform} = require('../index.js');
@@ -48,6 +50,7 @@ function transformToCode(
       experimentalImportSupport,
       globalPrefix: '__metro__',
       hot: false,
+      inlinePlatform,
       minify: false,
       platform,
       publicPath: 'test',
@@ -151,6 +154,19 @@ describe.each([false, true])(
 
       expect(code).toMatch(/\.OS\b/);
     });
+
+    test('does not inline without the inlinePlatform opt-in', () => {
+      // Metro sets this per build; consumers that only need platform-correct
+      // resolution (Jest) pass a platform without it and must keep `Platform`
+      // observable so it can be mocked.
+      const code = transformToCode(
+        "import {Platform} from 'react-native';\nconst os = Platform.OS;",
+        {inlinePlatform: false, experimentalImportSupport},
+      );
+
+      expect(code).toMatch(/\.OS\b/);
+      expect(code).not.toContain('"ios"');
+    });
   },
 );
 
diff --git a/packages/react-native-babel-transformer/src/index.js b/packages/react-native-babel-transformer/src/index.js
index a48f3a802736..a830c9cd1072 100644
--- a/packages/react-native-babel-transformer/src/index.js
+++ b/packages/react-native-babel-transformer/src/index.js
@@ -197,6 +197,8 @@ const transform /*: BabelTransformer['transform'] */ = ({
       name: 'metro',
       bundler: 'metro',
       platform: options.platform,
+      // $FlowFixMe[prop-missing] Remove suppression after next Metro release
+      inlinePlatform: options.inlinePlatform,
       unstable_transformProfile: options.unstable_transformProfile,
     },
     ast: true,